[maka]

Didn't notice it earlier but it might be a good idea to use some of those hotkeys without modifiers kamos. Like 1-4 +- alt is a way to keep your hand on 8 actions without even moving.

EG:
1: Heal self
2: Bandage self
3: Healpot
4: Heal scroll self

Alt + 1: Light Last
Alt + 2: XUO pre (what ever way you choose to do it, i often use bandages so its good to have it on alt +2)
Alt + 3: XUO last
Alt + 4: NOS Last

Adding the mouse we got:
Scroll Up: Arrow (not with last, but to target)
Scroll Down: SPECIAL (scripted) XUO precast macro.

Scroll Up + alt: Arrow last
Scroll Down + alt: Mana pot

You can then add anything (reflect, cut, aid) to your other mouse buttons (+-modifiers) without much problem, but when using the scroll, remember that you should only have macros that you can afford to cast more than once. Eg, you don't really want an XUO scroll last macro on the scroll cause if you happen to scroll up more than once, you are dead:p

That is why I wrote SPECIAL, cause if you want a dangerous macro on the scroll, make sure it doesn't run more than once.

Those are not entirely my [1v1] macros, but somewhat close. The basis is that if you are holding alt then you're ready to attack, if you let it go, you are in defense mode. You can also change them around if you find that your pinky is not fast enough to be on the VERY important heal macros. One idea to put on 1 is bandage self and XUO pre.